Alzheimer's disease is the most common cause of dementia. Although not all causes of Alzheimer's disease are known, experts do know that a small percentage are related to mutations of three genes, which can be passed down from parent to child. While several different genes are probably involved in Alzheimer's disease, one important gene that increases risk is apolipoprotein E4 (APOE). Alzheimer's disease is a progressive disorder that causes brain cells to waste away (degenerate) and die. Brain cell connections and the cells themselves degenerate and die, eventually destroying memory and other important mental functions. Memory loss and confusion are the main symptoms. No cure exists, but medication and management strategies may temporarily improve symptoms. Alzheimer's disease patients have plaques and tangles in their brains. Plaques are clumps of a protein called beta-amyloid, and tangles are fibrous tangles made up of tau protein. It's thought that these clumps damage healthy neurons and the fibers connecting them. Other genetic factors might make it more likely that people will develop Alzheimer's.
Benefits of HBOT :Hypoxia-lack of oxygen in the tissue has a major role in AD pathogenesis. The association between hypoxia and dementia emerged from epidemiological studies, showing increased incidence of dementia in ischemic stroke patients. Recent evidence suggests that AD patients present reduced cerebral perfusion, which can be detected in early stages of the disease, and declines further with disease progression. Furthermore, cerebral hypoperfusioncan lead to hypoxia, which has been shown to promote AD pathogenesis. The growing understanding of the importance of oxygen in brain functionality under normal and diseased conditions marks it as a key player in AD treatment. As such, HBOT emerges as a well-tolerated, safe and effective platform to enhance brain oxygenation.